Immunological Evaluation of Recurrent Implantation Failure


The Journal Reproductive Immunology: Open Access aims to spread knowledge and promote discussion through the publication of peer-reviewed, high quality research papers on all topics related to the reproductive immunology. The open access journal is published by Insight Medical Publishing who hosts open access peer-reviewed journals as well as organizes conferences that hosts the work of researchers in a manner that exemplifies the highest standards in research integrity.

We are delighted to share one of our recent published scientific communications with you titled “Evidence-based Update: Immunological Evaluation of Recurrent Implantation Failure”. The corresponding author Dr. Silvia Sánchez-Ramón has well demonstrated his research work and the following abstract says it:


Recurrent implantation failure (RIF) is generally defined as the failure to achieve clinical pregnancy after the transfer of at least 6 good quality embryos in fresh or frozen IVF cycles or of at least 4 embryos in two egg donations. Patients with RIF represents an heterogeneous group in which diverse immunological or inflammatory factors have been described, representing globally the more frequent known causes, including antiphospholipid syndrome or autoimmune thyroid disease, among others. However, there is a lack of evidence-based reviews focusing on inflammatory RIF (iRIF). We performed a systematic review of the published literature on iRIF from 1988 to July 2016, in order to build an updated evidence-based classification of immunological diagnostic tests and assigned recommendations accordingly. This review intends to offer a useful immunological workout of women suffering RIF from a multidisciplinary approach.

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Our Journal emphasizes high-level research and education. Original research articles, reviews, short communications, and letters to the editors in the field of Reproductive Immunology are welcome. Every effort is made to have a speedy and critical peer-review process. We always encourage new research works under the scope of our Journal.

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