Studying Genes and Proteins Together Sheds New Light on Colorectal Cancer


On behalf of the Journal of Colorectal Cancer: Open Access, as Editor-in-Chief, it is my distinct honour and privilege to inform you that, it’s been Six long years we have started the Journal, now we are celebrating the 6th Anniversary and we are privileged to welcome Cancer Society to our journal. As Editor-In-Chief it is my great pleasure and honour to welcome you to The Journal of Colorectal Cancer: Open Access, Opening Issue of the Year 2020.

The integrated study of genes and proteins, called proteogenomics, is a fairly new area of research intended to provide researchers with a greater understanding of biology one that cannot be gained by studying genes alone. The finding underscores how multiple types of treatment may be required to cure what appears outwardly as a single type of cancer, the researchers say. And it hints that the current cell-line models of human cancers, which showed patterns that differed from the tumor cells shed from human patients, need to be improved upon.

The Journal Opening Issue of the year in the 6th Volume which covers a wide variety of specialties including the CPTAC team began by collecting samples of blood, tumor tissue, and nearby normal tissue from 110 people with colon cancer. They then captured the sequences of all DNA, RNA, microRNA, and protein molecules in each sample. In addition, they looked at how many copies of each gene were present (gene copy number), the relative amounts of each protein (protein expression), and whether the proteins were chemically modified (protein phosphorylation). Submit here

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With regards,

Joseph Marreddy
Journal of Colorectal Cancer: Open Access
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