Treatments for Glomerulonephritis


Glomerulonephritis is a term used to refer to several kidney diseases (usually affecting both kidneys). Many of the diseases are characterised by inflammation either of the glomeruli or of the small blood vessels in the kidneys, hence the name, but not all diseases necessarily have an inflammatory component.

The nephritic syndrome is characterised by the finding of edema in a person with increased protein in the urine and decreased protein in the blood, with increased fat in the blood. Inflammation that affects the cells surrounding the glomerulus, podocytes, increases the permeability to proteins, resulting in an increase in excreted proteins.

The nephritic syndrome is characterised by blood in the urine (especially Red blood cell casts with dimorphic red blood cells) and a decrease in the amount of urine in the presence of hypertension.

Post-streptococcal glomerulonephritis. Glomerulonephritis may develop a week or two after recovery from a strep throat infection or, rarely, a skin infection (impetigo). To fight the infection, your body produces extra antibodies that can eventually settle in the glomeruli, causing inflammation.

Bacterial endocarditis. Bacteria occasionally can spread through your bloodstream and lodge in your heart, causing an infection of one or more of your heart valves. You're at greater risk of this condition if you have a heart defect, such as a damaged or artificial heart valve. 

Antibiotic therapy to prevent streptococcal infection. Steroids to suppress immunity. Provide high calories & Low protein, sodium & potassium diet. Monitor for sign of kidney failure, heart failure, and hypertensive encephalopathy.

Journal of Nephrology and Urology is an Open Access peer-reviewed publication that discusses current research and advancements in diagnosis and management of kidney disorders as well as related epidemiology, pathophysiology and molecular genetics.

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Maya Wilson
Editorial Assistant
Journal of Nephrology and Urology